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Assay Detail

CHEMBL945909

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Decrease in iron-induced H2O2 production
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Multi-target-directed ligands to combat neurodegenerative diseases.
Cavalli A, Bolognesi ML, Minarini A, Rosini M, Tumiatti V, Recanatini M, Melchiorre C.
J Med Chem (2008) 51 : 347 -372
PubMed 18181565 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.98 5.04

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL258420 1 5.04
CHEMBL257368 1 4.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL258420 IC50 = 9220.0 nM 5.04
CHEMBL257368 IC50 = 12000.0 nM 4.92