Assay Detail
Binding
CHEMBL945931
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Inhibition of rat mPGES1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.89 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL180650 | — | — | 1 | 6.89 |
| CHEMBL412099 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL180650 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL412099 | — | IC50 | > | 30000.0 | nM | - |