Assay Detail
Binding
CHEMBL946950
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of p38beta
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.96 | 6.16 |
| Ki | 2 | 6.58 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL271271 | — | — | 2 | 6.80 |
| CHEMBL273158 | — | — | 2 | 6.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL271271 | — | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL273158 | — | Ki | = | 440.0 | nM | 6.36 |
| CHEMBL271271 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL273158 | — | IC50 | = | 1800.0 | nM | 5.75 |