Assay Detail
Functional
CHEMBL946983
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human NCI-H460 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H460 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Histone deacetylase inhibitors: from bench to clinic.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.20 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL368036 | — | — | 1 | 5.70 |
| CHEMBL361643 | — | — | 1 | 4.70 |
| CHEMBL325676 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL368036 | — | EC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL361643 | — | EC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL325676 | — | EC50 | > | 50000.0 | nM | - |