Assay Detail
Functional
CHEMBL947142
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Inhibition of mouse SC9 cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | SC9 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Histone deacetylase inhibitors: from bench to clinic.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.31 | 4.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL270740 | — | — | 1 | 4.34 |
| CHEMBL270739 | — | — | 1 | 4.30 |
| CHEMBL406650 | — | — | 1 | 4.28 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | - |
| CHEMBL409847 | — | — | 1 | - |
| CHEMBL410636 | — | — | 1 | - |
| CHEMBL270476 | — | — | 1 | - |
| CHEMBL270893 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL270740 | — | IC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL270739 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL406650 | — | IC50 | = | 52000.0 | nM | 4.28 |
| CHEMBL98 | VORINOSTAT | IC50 | - | — | - | |
| CHEMBL409847 | — | IC50 | - | — | - | |
| CHEMBL410636 | — | IC50 | = | 317000.0 | nM | - |
| CHEMBL270476 | — | IC50 | = | 934000.0 | nM | - |
| CHEMBL270893 | — | IC50 | = | 555000.0 | nM | - |