Assay Detail

CHEMBL947566

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Functional

Cytotoxicity against multidrug-sensitive human SKOV3 cells by SRB assay

ChEMBL ↗

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Target

SK-OV-3 (CHEMBL614925) ↗

Open DB target context

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SK-OV-3 (CHEMBL614925) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target SK-OV-3

CHEMBL614925

Anchored from Assay target.

Protein identity SK-OV-3

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	SK-OV-3
Confidence	1 — Organism
Curated By	Autocuration

Target

SK-OV-3 (CHEMBL614925) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Mappain, a new cytotoxic prenylated stilbene from Macaranga mappa.

van Der Kaaden JE, Hemscheidt TK, Mooberry SL.
J Nat Prod (2001) 64 : 103 -105
PubMed 11170679 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.89	5.89

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL515325	MAPPAIN	—	1	5.89

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL515325	MAPPAIN	IC50	=	1300.0	nM	5.89