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Assay Detail

CHEMBL947575

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HCV protease
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepatitis C virus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Circumdatin G, a new alkaloid from the fungus Aspergillus ochraceus.
Dai J, Carté BK, Sidebottom PJ, Sek Yew AL, Ng S, Huang Y, Butler MS.
J Nat Prod (2001) 64 : 125 -126
PubMed 11170686 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.73 5.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL179197 1 5.11
CHEMBL294018 PATULIN 1 4.61
CHEMBL226090 MELLEIN 1 4.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL179197 IC50 = 7700.0 nM 5.11
CHEMBL294018 PATULIN IC50 = 24700.0 nM 4.61
CHEMBL226090 MELLEIN IC50 = 35000.0 nM 4.46