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Assay Detail

CHEMBL947977

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of FGFR by HTRF assay
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

3-amino-benzo[d]isoxazoles as novel multitargeted inhibitors of receptor tyrosine kinases.
Ji Z, Ahmed AA, Albert DH, Bouska JJ, Bousquet PF, Cunha GA, Diaz G, Glaser KB, Guo J, Harris CM, Li J, Marcotte PA, Moskey MD, Oie T, Pease L, Soni NB, Stewart KD, Davidsen SK, Michaelides MR.
J Med Chem (2008) 51 : 1231 -1241
PubMed 18260617 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Activity 2 - -
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL430090 1 5.52
CHEMBL270084 1 -
CHEMBL269884 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL430090 IC50 = 3000.0 nM 5.52
CHEMBL270084 Activity - -
CHEMBL269884 Activity - -