Assay Detail
Binding
CHEMBL948647
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bee venom PLA2
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Apis mellifera |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Phospholipase A2 inhibitors from marine organisms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.89 | 7.40 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463914 | MANOALIDE | — | 1 | 7.40 |
| CHEMBL487005 | SCALARADIAL | — | 1 | 7.16 |
| CHEMBL478091 | — | — | 1 | 6.70 |
| CHEMBL451037 | LUFFARIELLOLIDE | — | 1 | 6.64 |
| CHEMBL482592 | — | — | 1 | 6.55 |
| CHEMBL155085 | ILIMAQUINONE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463914 | MANOALIDE | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL487005 | SCALARADIAL | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL478091 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL451037 | LUFFARIELLOLIDE | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL482592 | — | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL155085 | ILIMAQUINONE | Activity | - | — | - |