Assay Detail
Functional
CHEMBL949110
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Inhibition of human MM96L cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MM96L |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Histone deacetylase inhibitors: from bench to clinic.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.70 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL99 | TRICHOSTATIN | 1.0 | 1 | 7.52 |
| CHEMBL101006 | — | — | 1 | 6.89 |
| CHEMBL318384 | — | — | 1 | 6.85 |
| CHEMBL103508 | — | — | 1 | 6.70 |
| CHEMBL103379 | — | — | 1 | 6.70 |
| CHEMBL323346 | — | — | 1 | 6.22 |
| CHEMBL103556 | — | — | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL99 | TRICHOSTATIN | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL101006 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL318384 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL103508 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL103379 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL323346 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL103556 | — | IC50 | = | 900.0 | nM | 6.05 |