Assay Detail
Binding
CHEMBL949120
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Inhibition of human rhinovirus 14 3C protease
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | rhinovirus B14 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.76 | 8.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL145753 | — | — | 1 | 8.35 |
| CHEMBL272994 | — | — | 1 | 7.19 |
| CHEMBL228200 | — | — | 1 | 6.77 |
| CHEMBL402559 | — | — | 1 | 6.16 |
| CHEMBL256829 | — | — | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL145753 | — | Ki | = | 4.5 | nM | 8.35 |
| CHEMBL272994 | — | Ki | = | 65.0 | nM | 7.19 |
| CHEMBL228200 | — | Ki | = | 170.0 | nM | 6.77 |
| CHEMBL402559 | — | Ki | = | 700.0 | nM | 6.16 |
| CHEMBL256829 | — | Ki | = | 4700.0 | nM | 5.33 |