Assay Detail
Functional
CHEMBL949121
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Antiviral activity against human rhinovirus 14
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | rhinovirus B14 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.62 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL145753 | — | — | 1 | 6.47 |
| CHEMBL272994 | — | — | 1 | 5.50 |
| CHEMBL228200 | — | — | 1 | 5.40 |
| CHEMBL402559 | — | — | 1 | 5.10 |
| CHEMBL256829 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL145753 | — | EC50 | = | 340.0 | nM | 6.47 |
| CHEMBL272994 | — | EC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL228200 | — | EC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL402559 | — | EC50 | = | 7900.0 | nM | 5.10 |
| CHEMBL256829 | — | EC50 | > | 10000.0 | nM | - |