Assay Detail
Functional
CHEMBL949538
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Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 by LDH assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.11 | 7.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL509157 | — | — | 1 | 7.54 |
| CHEMBL487277 | — | — | 1 | 7.26 |
| CHEMBL58510 | CHLOROQUINE PHOSPHATE | 4.0 | 1 | 6.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL509157 | — | IC50 | = | 28.9 | nM | 7.54 |
| CHEMBL487277 | — | IC50 | = | 54.7 | nM | 7.26 |
| CHEMBL58510 | CHLOROQUINE PHOSPHATE | IC50 | = | 293.5 | nM | 6.53 |