Assay Detail
Binding
CHEMBL949544
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Inhibition of Src
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Proto-oncogene tyrosine-protein kinase Src (CHEMBL267) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of a potent and selective c-Kit inhibitor for the treatment of inflammatory diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.99 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL259247 | — | — | 1 | 6.62 |
| CHEMBL512840 | — | — | 1 | 5.92 |
| CHEMBL469882 | — | — | 1 | 5.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL259247 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL512840 | — | IC50 | = | 1210.0 | nM | 5.92 |
| CHEMBL469882 | — | IC50 | = | 3760.0 | nM | 5.42 |