Assay Detail
Functional
CHEMBL949594
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Antiplasmodial activity after 24 hrs against chloroquine-sensitive Plasmodium falciparum Nigerian by [3H]hypoxanthine uptake
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive acridone alkaloids from Swinglea glutinosa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.50 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL58510 | CHLOROQUINE PHOSPHATE | 4.0 | 1 | 7.16 |
| CHEMBL463652 | GLYCOCITRINE-IV | — | 1 | 5.60 |
| CHEMBL464846 | — | — | 1 | 5.28 |
| CHEMBL447169 | — | — | 1 | 4.96 |
| CHEMBL465847 | CITRUSININE-II | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL58510 | CHLOROQUINE PHOSPHATE | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL463652 | GLYCOCITRINE-IV | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL464846 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL447169 | — | IC50 | = | 11100.0 | nM | 4.96 |
| CHEMBL465847 | CITRUSININE-II | IC50 | = | 33000.0 | nM | 4.48 |