Assay Detail
Functional
CHEMBL949596
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Antiplasmodial activity after 24 hrs against chloroquine-resistant Plasmodium falciparum FcM29 by [3H]hypoxanthine uptake
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive acridone alkaloids from Swinglea glutinosa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.34 | 6.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL58510 | CHLOROQUINE PHOSPHATE | 4.0 | 1 | 6.35 |
| CHEMBL463652 | GLYCOCITRINE-IV | — | 1 | 5.70 |
| CHEMBL464846 | — | — | 1 | 5.10 |
| CHEMBL447169 | — | — | 1 | 4.99 |
| CHEMBL465847 | CITRUSININE-II | — | 1 | 4.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL58510 | CHLOROQUINE PHOSPHATE | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL463652 | GLYCOCITRINE-IV | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL464846 | — | IC50 | = | 7900.0 | nM | 5.10 |
| CHEMBL447169 | — | IC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL465847 | CITRUSININE-II | IC50 | = | 27100.0 | nM | 4.57 |