Assay Detail
Binding
CHEMBL950135
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In vivo inhibition of trypsin-like activity of 20S proteasome
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Vinyl ester-based cyclic peptide proteasome inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.47 | 6.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL257878 | — | — | 1 | 6.71 |
| CHEMBL255202 | — | — | 1 | 6.36 |
| CHEMBL250260 | — | — | 1 | 6.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL257878 | — | IC50 | = | 197.0 | nM | 6.71 |
| CHEMBL255202 | — | IC50 | = | 436.0 | nM | 6.36 |
| CHEMBL250260 | — | IC50 | = | 473.0 | nM | 6.33 |