Assay Detail
Binding
CHEMBL950232
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human VEGFR1
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Vascular endothelial growth factor receptor 1 (CHEMBL1868) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 2 | - | - |
| IC50 | 1 | 7.14 | 7.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL271188 | — | — | 1 | 7.14 |
| CHEMBL272198 | — | — | 1 | - |
| CHEMBL271984 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL271188 | — | IC50 | = | 73.0 | nM | 7.14 |
| CHEMBL272198 | — | Activity | - | — | - | |
| CHEMBL271984 | — | Activity | - | — | - |