Assay Detail
Binding
CHEMBL950240
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Lyn
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.06 | 7.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL272198 | — | — | 1 | 7.57 |
| CHEMBL271984 | — | — | 1 | 7.06 |
| CHEMBL271188 | — | — | 1 | 6.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL272198 | — | IC50 | = | 27.0 | nM | 7.57 |
| CHEMBL271984 | — | IC50 | = | 88.0 | nM | 7.06 |
| CHEMBL271188 | — | IC50 | = | 275.0 | nM | 6.56 |