Assay Detail
Binding
CHEMBL951138
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of pig brain alpha-beta-tubulin polymerization
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Conformational preferences of natural and C3-modified epothilones in aqueous solution.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.30 | 5.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL329993 | EPOTHILONE A | — | 1 | 5.34 |
| CHEMBL411694 | 3-DEOXY-2,3-DIDEHYDRO-EPO A | — | 1 | 5.32 |
| CHEMBL261834 | 3-DEOXY-EPO A | — | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL329993 | EPOTHILONE A | EC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL411694 | 3-DEOXY-2,3-DIDEHYDRO-EPO A | EC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL261834 | 3-DEOXY-EPO A | EC50 | = | 5600.0 | nM | 5.25 |