Assay Detail
ADMET
CHEMBL952424
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Cytotoxicity against human K562 cells by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.66 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL487277 | — | — | 1 | 7.75 |
| CHEMBL509157 | — | — | 1 | 7.74 |
| CHEMBL58510 | CHLOROQUINE PHOSPHATE | 4.0 | 1 | 7.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL487277 | — | IC50 | = | 17.59 | nM | 7.75 |
| CHEMBL509157 | — | IC50 | = | 18.07 | nM | 7.74 |
| CHEMBL58510 | CHLOROQUINE PHOSPHATE | IC50 | = | 31.83 | nM | 7.50 |