Assay Detail
Functional
CHEMBL952479
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Antiviral activity against HBV in human HepW10 cells assessed as inhibition of viral pre genomic RNA replication
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Cell Type | HepW10 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Unique antiviral mechanism discovered in anti-hepatitis B virus research with a natural product analogue.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.40 | 6.40 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL369673 | — | — | 1 | 6.40 |
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL369673 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL141 | LAMIVUDINE | Activity | - | — | - |