Assay Detail
Functional
CHEMBL952494
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HBV promoter in human HepG2(2.2.15) cells by luciferase reporter gene assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Unique antiviral mechanism discovered in anti-hepatitis B virus research with a natural product analogue.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.10 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL369673 | — | — | 1 | 7.10 |
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | 7.10 |
| CHEMBL367646 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL369673 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL141 | LAMIVUDINE | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL367646 | — | IC50 | = | 80.0 | nM | 7.10 |