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Assay Detail

CHEMBL952594

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]Ro15-1788 from rat GABAA alpha-1-beta-2-gamma-2S receptor expressed in HEK293 cells by liquid scintillation counting
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Cell Type HEK293
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Proximity-accelerated chemical coupling reaction in the benzodiazepine-binding site of gamma-aminobutyric acid type A receptors: superposition of different allosteric modulators.
Tan KR, Gonthier A, Baur R, Ernst M, Goeldner M, Sigel E.
J Biol Chem (2007) 282 : 26316 -26325
PubMed 17626010 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL485829 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL485829 Ki = 10.0 nM 8.00