Assay Detail
Binding
CHEMBL953080
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ADAMTS1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
A disintegrin and metalloproteinase with thrombospondin motifs 1 (CHEMBL5133) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.11 | 5.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL495502 | — | — | 1 | 5.11 |
| CHEMBL207305 | — | — | 1 | 5.11 |
| CHEMBL253275 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL495502 | — | Ki | = | 7800.0 | nM | 5.11 |
| CHEMBL207305 | — | Ki | = | 7800.0 | nM | 5.11 |
| CHEMBL253275 | — | Ki | > | 1000.0 | nM | - |