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Assay Detail

CHEMBL953090

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of BMP1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Bone morphogenetic protein 1 (CHEMBL3898)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge.
Georgiadis D, Yiotakis A.
Bioorg Med Chem (2008) 16 : 8781 -8794
PubMed 18790648 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.67 7.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL389020 1 7.96
CHEMBL262758 1 7.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL389020 Ki = 11.0 nM 7.96
CHEMBL262758 Ki = 43.0 nM 7.37