Assay Detail
Binding
CHEMBL953091
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Inhibition of bovine aggrecanase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.18 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL24595 | — | — | 1 | 8.52 |
| CHEMBL523956 | — | — | 1 | 8.10 |
| CHEMBL24398 | — | — | 1 | 7.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL24595 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL523956 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL24398 | — | IC50 | = | 12.0 | nM | 7.92 |