Assay Detail
Binding
CHEMBL954052
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of radioligand from human cloned 5HT1F receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of potent, orally bioavailable, selective 5-HT1A/B/D receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.15 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL497963 | — | — | 1 | 6.30 |
| CHEMBL522708 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL497963 | — | Ki | = | 501.19 | nM | 6.30 |
| CHEMBL522708 | — | Ki | = | 1000.0 | nM | 6.00 |