Assay Detail
Binding
CHEMBL954307
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Inhibition of trypsin-like activity of 20S proteasome beta 2 subunit by cell based assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
New cyclic peptide proteasome inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.20 | 5.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL462403 | — | — | 1 | 5.23 |
| CHEMBL500747 | — | — | 1 | 5.16 |
| CHEMBL457409 | — | — | 1 | - |
| CHEMBL445424 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL462403 | — | IC50 | = | 5830.0 | nM | 5.23 |
| CHEMBL500747 | — | IC50 | = | 6940.0 | nM | 5.16 |
| CHEMBL457409 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL445424 | — | IC50 | > | 10000.0 | nM | - |