Assay Detail
Binding
CHEMBL955705
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Inhibition of PSMA in human LNCaP cell extract using [3H]NAAG by fluorescence-based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | LNCaP |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Radiohalogenated prostate-specific membrane antigen (PSMA)-based ureas as imaging agents for prostate cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.99 | 11.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL510924 | — | — | 1 | 11.00 |
| CHEMBL454897 | — | — | 1 | 9.71 |
| CHEMBL454898 | — | — | 1 | 9.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL510924 | — | Ki | = | 0.01 | nM | 11.00 |
| CHEMBL454897 | — | Ki | = | 0.194 | nM | 9.71 |
| CHEMBL454898 | — | Ki | = | 0.557 | nM | 9.25 |