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Assay Detail

CHEMBL955768

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Binding
Inhibition of Clostridium perfringens neuraminidase
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Clostridium perfringens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pterocarpans and flavanones from Sophora flavescens displaying potent neuraminidase inhibition.
Ryu YB, Curtis-Long MJ, Kim JH, Jeong SH, Yang MS, Lee KW, Lee WS, Park KH.
Bioorg Med Chem Lett (2008) 18 : 6046 -6049
PubMed 18938076 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 11 4.98 5.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL242128 PTEROCARPIN 1 5.85
CHEMBL334918 MAACKIAIN 1 5.50
CHEMBL509486 KUSHENOL T 1 4.92
CHEMBL243148 SOPHORAFLAVANONE G 1 4.87
CHEMBL455679 KUSHENOL A 1 4.83
CHEMBL243796 KURARINONE 1 4.82
CHEMBL464825 MANGIFERIN 1 4.79
CHEMBL455667 KURARINOL 1 4.77
CHEMBL454647 NORKURARINOL 1 4.74
CHEMBL453642 LEACHIANONE A 1 4.70
CHEMBL454878 TRIFOLIRHIZIN 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL242128 PTEROCARPIN IC50 = 1400.0 nM 5.85
CHEMBL334918 MAACKIAIN IC50 = 3200.0 nM 5.50
CHEMBL509486 KUSHENOL T IC50 = 12100.0 nM 4.92
CHEMBL243148 SOPHORAFLAVANONE G IC50 = 13500.0 nM 4.87
CHEMBL455679 KUSHENOL A IC50 = 14800.0 nM 4.83
CHEMBL243796 KURARINONE IC50 = 15100.0 nM 4.82
CHEMBL464825 MANGIFERIN IC50 = 16200.0 nM 4.79
CHEMBL455667 KURARINOL IC50 = 17000.0 nM 4.77
CHEMBL454647 NORKURARINOL IC50 = 18300.0 nM 4.74
CHEMBL453642 LEACHIANONE A IC50 = 20100.0 nM 4.70
CHEMBL454878 TRIFOLIRHIZIN IC50 = 237000.0 nM -