Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL955769

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Clostridium perfringens neuraminidase by Lineweaver-Burke plot
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Clostridium perfringens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pterocarpans and flavanones from Sophora flavescens displaying potent neuraminidase inhibition.
Ryu YB, Curtis-Long MJ, Kim JH, Jeong SH, Yang MS, Lee KW, Lee WS, Park KH.
Bioorg Med Chem Lett (2008) 18 : 6046 -6049
PubMed 18938076 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 11 4.94 5.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL242128 PTEROCARPIN 1 5.77
CHEMBL334918 MAACKIAIN 1 5.68
CHEMBL509486 KUSHENOL T 1 4.97
CHEMBL455679 KUSHENOL A 1 4.77
CHEMBL243796 KURARINONE 1 4.73
CHEMBL455667 KURARINOL 1 4.71
CHEMBL243148 SOPHORAFLAVANONE G 1 4.70
CHEMBL454647 NORKURARINOL 1 4.64
CHEMBL453642 LEACHIANONE A 1 4.52
CHEMBL454878 TRIFOLIRHIZIN 1 -
CHEMBL464825 MANGIFERIN 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL242128 PTEROCARPIN Ki = 1700.0 nM 5.77
CHEMBL334918 MAACKIAIN Ki = 2100.0 nM 5.68
CHEMBL509486 KUSHENOL T Ki = 10800.0 nM 4.97
CHEMBL455679 KUSHENOL A Ki = 17100.0 nM 4.77
CHEMBL243796 KURARINONE Ki = 18800.0 nM 4.73
CHEMBL455667 KURARINOL Ki = 19700.0 nM 4.71
CHEMBL243148 SOPHORAFLAVANONE G Ki = 20000.0 nM 4.70
CHEMBL454647 NORKURARINOL Ki = 22700.0 nM 4.64
CHEMBL453642 LEACHIANONE A Ki = 30400.0 nM 4.52
CHEMBL454878 TRIFOLIRHIZIN Ki = 190000.0 nM -
CHEMBL464825 MANGIFERIN Ki - -