Assay Detail
Binding
CHEMBL955798
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PDGFRa
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (CHEMBL4766) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Pyrrolo-pyrimidones: a novel class of MK2 inhibitors with potent cellular activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.59 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL461139 | — | — | 1 | 5.70 |
| CHEMBL461140 | — | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL461139 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL461140 | — | IC50 | = | 3300.0 | nM | 5.48 |