Assay Detail

CHEMBL956407

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiparasitic activity against Plasmodium falciparum

ChEMBL ↗

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Target

Plasmodium falciparum (CHEMBL364) ↗

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Primary target Plasmodium falciparum

CHEMBL364

Anchored from Assay target.

Protein identity Plasmodium falciparum

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Plasmodium falciparum
Confidence	1 — Organism
Curated By	Autocuration

Target

Plasmodium falciparum (CHEMBL364) ↗

Type	ORGANISM
Organism	Plasmodium falciparum

Publication

Mass spectrometry-based systems approach for identification of inhibitors of Plasmodium falciparum fatty acid synthase.

Sharma S, Sharma SK, Modak R, Karmodiya K, Surolia N, Surolia A.
Antimicrob Agents Chemother (2007) 51 : 2552 -2558
PubMed 17485508 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.70	4.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL45627	CERULENIN	—	1	4.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL45627	CERULENIN	IC50	=	20000.0	nM	4.70