Assay Detail
Binding
CHEMBL956491
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human HEK293 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): a high-affinity 5-HT2A receptor-selective agonist radioligand.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.70 | 8.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL263881 | LYSERGIDE | 2.0 | 1 | 8.46 |
| CHEMBL6616 | — | — | 1 | 7.85 |
| CHEMBL18786 | CINANSERIN | 2.0 | 1 | 7.66 |
| CHEMBL39 | SEROTONIN | 3.0 | 1 | 6.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL263881 | LYSERGIDE | Ki | = | 3.5 | nM | 8.46 |
| CHEMBL6616 | — | Ki | = | 14.0 | nM | 7.85 |
| CHEMBL18786 | CINANSERIN | Ki | = | 22.0 | nM | 7.66 |
| CHEMBL39 | SEROTONIN | Ki | = | 150.0 | nM | 6.82 |