Assay Detail
Functional
CHEMBL956769
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human PC3 cells by resazurin reduction test
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, cytotoxicity, and haemolytic activity of chacotrioside lupane-type neosaponins and their germanicane-type rearrangement products.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.76 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL505539 | — | — | 1 | 5.00 |
| CHEMBL476957 | — | — | 1 | 4.89 |
| CHEMBL269277 | BETULINIC ACID | 1.0 | 1 | 4.40 |
| CHEMBL508839 | — | — | 1 | - |
| CHEMBL507580 | — | — | 1 | - |
| CHEMBL506403 | — | — | 1 | - |
| CHEMBL522595 | — | — | 1 | - |
| CHEMBL496855 | ALLOBETULIN | — | 1 | - |
| CHEMBL23236 | BETULIN | — | 1 | - |
| CHEMBL289191 | LUPEOL | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL505539 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL476957 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL269277 | BETULINIC ACID | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL508839 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL507580 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL506403 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL522595 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL496855 | ALLOBETULIN | IC50 | > | 50000.0 | nM | - |
| CHEMBL23236 | BETULIN | IC50 | - | — | - | |
| CHEMBL289191 | LUPEOL | IC50 | > | 50000.0 | nM | - |