Assay Detail
Binding
CHEMBL957138
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PERV reverse transcriptase from Kagoshima pig DRK4 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Porcine endogenous retrovirus |
| Cell Type | DRK4 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.24 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL193952 | ZIDOVUDINE TRIPHOSPHATE | -1.0 | 1 | 7.70 |
| CHEMBL485652 | STAVUDINE TRIPHOSPHATE | -1.0 | 1 | 6.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL193952 | ZIDOVUDINE TRIPHOSPHATE | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL485652 | STAVUDINE TRIPHOSPHATE | IC50 | = | 170.0 | nM | 6.77 |