Assay Detail
Binding
CHEMBL957782
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Stimulation of rabbit muscle actin polymerization by centrifugation assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Tissue | Muscle tissue |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.21 | 5.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL257166 | JASPAMIDE | — | 1 | 5.72 |
| CHEMBL505302 | HECTOCHLORIN | — | 1 | 4.70 |
| CHEMBL508049 | LYNGBYABELLIN B | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL257166 | JASPAMIDE | EC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL505302 | HECTOCHLORIN | EC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL508049 | LYNGBYABELLIN B | EC50 | > | 50000.0 | nM | - |