Assay Detail
Binding
CHEMBL957785
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of FITC-phalloidin from rabbit muscle actin polymer after 1 hr by fluorescence analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Tissue | Muscle tissue |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.19 | 5.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL257166 | JASPAMIDE | — | 1 | 5.19 |
| CHEMBL505302 | HECTOCHLORIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL257166 | JASPAMIDE | EC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL505302 | HECTOCHLORIN | EC50 | > | 60000.0 | nM | - |