Assay Detail
Binding
CHEMBL958728
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Binding affinity to DPP4
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Recent developments in fragment-based drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.02 | 7.64 |
| Ki | 2 | 7.04 | 8.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL237337 | — | — | 1 | 8.37 |
| CHEMBL381806 | — | — | 1 | 7.64 |
| CHEMBL383705 | — | — | 1 | 5.70 |
| CHEMBL382127 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL237337 | — | Ki | = | 4.3 | nM | 8.37 |
| CHEMBL381806 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL383705 | — | Ki | = | 2000.0 | nM | 5.70 |
| CHEMBL382127 | — | IC50 | = | 40000.0 | nM | 4.40 |