Assay Detail
Binding
CHEMBL958732
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Inhibition of PNMT
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Target
Phenylethanolamine N-methyltransferase (CHEMBL4617) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent developments in fragment-based drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.04 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL287837 | — | — | 1 | 8.52 |
| CHEMBL175519 | — | — | 1 | 7.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL287837 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL175519 | — | IC50 | = | 28.0 | nM | 7.55 |