Assay Detail

CHEMBL959523

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of Leishmania mexicana squalene synthase

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Leishmania mexicana
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Quinuclidine derivatives as potential antiparasitics.

Cammerer SB, Jimenez C, Jones S, Gros L, Lorente SO, Rodrigues C, Rodrigues JC, Caldera A, Ruiz Perez LM, da Souza W, Kaiser M, Brun R, Urbina JA, Gonzalez Pacanowska D, Gilbert IH.
Antimicrob Agents Chemother (2007) 51 : 4049 -4061
PubMed 17709461 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	7.92	7.92

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL279261	—	—	1	7.92

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL279261	—	Ki	=	12.0	nM	7.92