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Assay Detail

CHEMBL959524

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Trypanosoma cruzi squalene synthase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Trypanosoma cruzi
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Farnesyltransferase, putative (CHEMBL5220)
Type SINGLE PROTEIN
Organism Trypanosoma cruzi (strain CL Brener)

Publication

Quinuclidine derivatives as potential antiparasitics.
Cammerer SB, Jimenez C, Jones S, Gros L, Lorente SO, Rodrigues C, Rodrigues JC, Caldera A, Ruiz Perez LM, da Souza W, Kaiser M, Brun R, Urbina JA, Gonzalez Pacanowska D, Gilbert IH.
Antimicrob Agents Chemother (2007) 51 : 4049 -4061
PubMed 17709461 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.21 7.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL279261 1 7.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL279261 Ki = 62.0 nM 7.21