Assay Detail
Binding
CHEMBL959586
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cathepsin C in human B721 cells by FACS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | B721 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Substrate optimization for monitoring cathepsin C activity in live cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.98 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL514348 | — | — | 1 | 7.16 |
| CHEMBL486232 | — | — | 1 | 5.58 |
| CHEMBL212521 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL514348 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL486232 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL212521 | — | IC50 | = | 6100.0 | nM | 5.21 |