Assay Detail
Binding
CHEMBL960207
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Inhibition of Sprague-Dawley rat cytosolic alcohol dehydrogenase
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Elgonica-Dimers A and B, Two Potent Alcohol Metabolism Inhibitory Constituents of Aloe arborescens
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.86 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL494494 | — | — | 1 | 7.96 |
| CHEMBL449188 | — | — | 1 | 7.26 |
| CHEMBL15967 | PYRAZOLE | — | 1 | 5.01 |
| CHEMBL40275 | ALOE-EMODIN | — | 1 | 4.61 |
| CHEMBL518845 | ALOENIN | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL494494 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL449188 | — | IC50 | = | 55.0 | nM | 7.26 |
| CHEMBL15967 | PYRAZOLE | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL40275 | ALOE-EMODIN | IC50 | = | 24400.0 | nM | 4.61 |
| CHEMBL518845 | ALOENIN | IC50 | = | 33100.0 | nM | 4.48 |