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Assay Detail

CHEMBL961906

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Functional
Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Publication

Oxidation, reduction, and methylation of carnosic acid by Nocardia.
Hosny M, Johnson HA, Ueltschy AK, Rosazza JP.
J Nat Prod (2002) 65 : 1266 -1269
PubMed 12350144 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 4.24 4.42

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL307145 PYROGALLOL -1.0 1 4.42
CHEMBL7983 PROPYL GALLATE 1.0 1 4.34
CHEMBL484853 CARNOSIC ACID 1 4.27
CHEMBL483017 1 4.18
CHEMBL196 ASCORBIC ACID 4.0 1 4.17
CHEMBL483016 1 4.08
CHEMBL218693 CARNOSOL 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL307145 PYROGALLOL IC50 = 37800.0 nM 4.42
CHEMBL7983 PROPYL GALLATE IC50 = 46100.0 nM 4.34
CHEMBL484853 CARNOSIC ACID IC50 = 53300.0 nM 4.27
CHEMBL483017 IC50 = 66000.0 nM 4.18
CHEMBL196 ASCORBIC ACID IC50 = 66800.0 nM 4.17
CHEMBL483016 IC50 = 83400.0 nM 4.08
CHEMBL218693 CARNOSOL IC50 = 114000.0 nM -