Assay Detail
Binding
CHEMBL962295
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Binding affinity to transmembrane alpha-helix of glycophorin A 2G/2I mutant by surface plasmon resonance method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Interaction of ladder-shaped polyethers with transmembrane alpha-helix of glycophorin A as evidenced by saturation transfer difference NMR and surface plasmon resonance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 4.39 | 5.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL500181 | — | — | 1 | 5.11 |
| CHEMBL1077126 | YESSOTOXIN | — | 1 | 4.07 |
| CHEMBL1077121 | DESULFATED YESSOTOXIN | — | 1 | 4.00 |
| CHEMBL506695 | — | — | 1 | - |
| CHEMBL471346 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL500181 | — | Kd | = | 7700.0 | nM | 5.11 |
| CHEMBL1077126 | YESSOTOXIN | Kd | = | 85000.0 | nM | 4.07 |
| CHEMBL1077121 | DESULFATED YESSOTOXIN | Kd | = | 99000.0 | nM | 4.00 |
| CHEMBL506695 | — | Kd | = | 150000.0 | nM | - |
| CHEMBL471346 | — | Kd | = | 860000.0 | nM | - |