Assay Detail
Functional
CHEMBL962448
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of T cell mitogen-induced blastogenesis in human PBMC after 4 days
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PBMC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel derivatives of 6-mercaptopurine: synthesis, characterization and antiproliferative activities of S-allylthio-mercaptopurines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.74 | 6.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1425 | MERCAPTOPURINE ANHYDROUS | 4.0 | 1 | 6.83 |
| CHEMBL1542 | AZATHIOPRINE | 4.0 | 1 | 6.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1425 | MERCAPTOPURINE ANHYDROUS | IC50 | = | 149.5 | nM | 6.83 |
| CHEMBL1542 | AZATHIOPRINE | IC50 | = | 230.4 | nM | 6.64 |