Assay Detail
Functional
CHEMBL962450
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Cytotoxicity against human K562 cells assessed as cell viability after 72 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
(+/-)-3,4-Dihydroxy-8,9-methylenedioxypterocarpan and derivatives: cytotoxic effect on human leukemia cell lines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.67 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL455617 | — | — | 1 | 5.82 |
| CHEMBL454850 | — | — | 1 | 5.52 |
| CHEMBL477455 | — | — | 1 | - |
| CHEMBL445279 | (+)-MAACKIAIN | — | 1 | - |
| CHEMBL476604 | — | — | 1 | - |
| CHEMBL476857 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL455617 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL454850 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL477455 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL445279 | (+)-MAACKIAIN | IC50 | > | 50000.0 | nM | - |
| CHEMBL476604 | — | IC50 | - | — | - | |
| CHEMBL476857 | — | IC50 | - | — | - |