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Assay Detail

CHEMBL962678

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by spectrophotometry
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Publication

2,3,4-Trimethyl-5,7-dihydroxy-2,3-dihydrobenzofuran, a novel antioxidant, from Penicillium citrinum F5.
Chen CH, Shaw CY, Chen CC, Tsai YC.
J Nat Prod (2002) 65 : 740 -741
PubMed 12027755 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 4.98 5.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1461 GENTISIC ACID 1 5.37
CHEMBL153 TROLOX 1 5.06
CHEMBL196 ASCORBIC ACID 4.0 1 5.05
CHEMBL463315 1 4.98
CHEMBL608 PROBUCOL 4.0 1 4.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1461 GENTISIC ACID IC50 = 4260.0 nM 5.37
CHEMBL153 TROLOX IC50 = 8770.0 nM 5.06
CHEMBL196 ASCORBIC ACID IC50 = 8920.0 nM 5.05
CHEMBL463315 IC50 = 10390.0 nM 4.98
CHEMBL608 PROBUCOL IC50 = 36110.0 nM 4.44